ICECUBE是一种用于检测1 GEV和1 PEV之间大气和天体中微子的光学传感器的立方公斤阵列，该阵列已部署1.45 km至2.45 km的南极的冰盖表面以下1.45 km至2.45 km。来自ICE探测器的事件的分类和重建在ICeCube数据分析中起着核心作用。重建和分类事件是一个挑战，这是由于探测器的几何形状，不均匀的散射和冰中光的吸收，并且低于100 GEV的光，每个事件产生的信号光子数量相对较少。为了应对这一挑战，可以将ICECUBE事件表示为点云图形，并将图形神经网络（GNN）作为分类和重建方法。 GNN能够将中微子事件与宇宙射线背景区分开，对不同的中微子事件类型进行分类，并重建沉积的能量，方向和相互作用顶点。基于仿真，我们提供了1-100 GEV能量范围的比较与当前ICECUBE分析中使用的当前最新最大似然技术，包括已知系统不确定性的影响。对于中微子事件分类，与当前的IceCube方法相比，GNN以固定的假阳性速率（FPR）提高了信号效率的18％。另外，GNN在固定信号效率下将FPR的降低超过8（低于半百分比）。对于能源，方向和相互作用顶点的重建，与当前最大似然技术相比，分辨率平均提高了13％-20％。当在GPU上运行时，GNN能够以几乎是2.7 kHz的中位数ICECUBE触发速率的速率处理ICECUBE事件，这打开了在在线搜索瞬态事件中使用低能量中微子的可能性。

基于快速的神经形态的视觉传感器（动态视觉传感器，DVS）可以与基于较慢的帧的传感器组合，以实现比使用例如固定运动近似的传统方法更高质量的帧间内插。光流。在这项工作中，我们展示了一个新的高级事件模拟器，可以产生由相机钻机录制的现实场景，该仪器具有位于固定偏移的任意数量的传感器。它包括具有现实图像质量降低效果的新型可配置帧的图像传感器模型，以及具有更精确的特性的扩展DVS模型。我们使用我们的模拟器培训一个新的重建模型，专为高FPS视频的端到端重建而设计。与以前发表的方法不同，我们的方法不需要帧和DVS相机具有相同的光学，位置或相机分辨率。它还不限于物体与传感器的固定距离。我们表明我们的模拟器生成的数据可用于训练我们的新模型，导致在与最先进的公共数据集上的公共数据集中的重建图像。我们还向传感器展示了真实传感器记录的数据。

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

The SNMMI Artificial Intelligence (SNMMI-AI) Summit, organized by the SNMMI AI Task Force, took place in Bethesda, MD on March 21-22, 2022. It brought together various community members and stakeholders from academia, healthcare, industry, patient representatives, and government (NIH, FDA), and considered various key themes to envision and facilitate a bright future for routine, trustworthy use of AI in nuclear medicine. In what follows, essential issues, challenges, controversies and findings emphasized in the meeting are summarized.

为了利用同一场景的视频框架中的高时间相关性，使用基于块的运动估计和补偿技术从已经编码的参考帧中预测了当前帧。尽管这种方法可以有效利用移动对象的翻译运动，但它容易受到其他类型的仿射运动和对象遮挡/除含量的影响。最近，深度学习已被用来模拟人类姿势的高级结构，以从短视频中的特定动作中进行，然后通过使用生成的对抗网络（GAN）来预测姿势，从而在未来的时间内生成虚拟框架。因此，建模人姿势的高级结构能够通过预测人类的行为并确定其轨迹来利用语义相关性。视频监视应用程序将受益，因为可以通过估算人类姿势轨迹并通过语义相关性产生未来的框架来压缩存储的大监视数据。本文通过从已经编码的框架中对人姿势进行建模并在当前时间使用生成的框架来探讨一种新的视频编码方式。预计所提出的方法可以通过预测包含具有较低残差的移动对象的块来克服传统向后引用框架的局限性。实验结果表明，提出的方法平均可以实现高达2.83 dB PSNR增益和25.93 \％比特率的节省，用于高运动视频序列

通过利用和适应到目前为止获得的知识，人类具有识别和区分他们不熟悉的实例的天生能力。重要的是，他们实现了这一目标，而不会在早期学习中恶化表现。受此启发，我们识别并制定了NCDWF的新的，务实的问题设置：新颖的类发现而无需忘记，哪个任务是机器学习模型从未标记的数据中逐步发现实例的新颖类别，同时在先前看到的类别上保持其性能。我们提出1）一种生成伪内表示的方法，该表示的代理（不再可用）标记的数据，从而减轻遗忘的遗忘，2）基于相互信息的正常化程序，可以增强对新型类别的无聊发现，而3）a 3）当测试数据包含所见类别和看不见的类别的实例时，简单的已知类标识符可以有助于广义推断。我们介绍了基于CIFAR-10，CIFAR-100和IMAGENET-1000的实验协议，以衡量知识保留和新型类发现之间的权衡。我们广泛的评估表明，现有的模型在确定新类别的同时灾难性地忘记了先前看到的类别，而我们的方法能够有效地在竞争目标之间平衡。我们希望我们的工作能够吸引对这个新确定的实用问题设定的进一步研究。

超越地球轨道的人类空间勘探将涉及大量距离和持续时间的任务。为了有效减轻无数空间健康危害，数据和空间健康系统的范式转移是实现地球独立性的，而不是Earth-Reliance所必需的。有希望在生物学和健康的人工智能和机器学习领域的发展可以解决这些需求。我们提出了一个适当的自主和智能精密空间健康系统，可以监控，汇总和评估生物医学状态;分析和预测个性化不良健康结果;适应并响应新累积的数据;并提供对其船员医务人员的个人深度空间机组人员和迭代决策支持的预防性，可操作和及时的见解。在这里，我们介绍了美国国家航空航天局组织的研讨会的建议摘要，以便在太空生物学和健康中未来的人工智能应用。在未来十年，生物监测技术，生物标志科学，航天器硬件，智能软件和简化的数据管理必须成熟，并编织成精确的空间健康系统，以使人类在深空中茁壮成长。

空间生物学研究旨在了解太空飞行对生物的根本影响，制定支持深度空间探索的基础知识，最终生物工程航天器和栖息地稳定植物，农作物，微生物，动物和人类的生态系统，为持续的多行星寿命稳定。要提高这些目标，该领域利用了来自星空和地下模拟研究的实验，平台，数据和模型生物。由于研究扩展到低地球轨道之外，实验和平台必须是最大自主，光，敏捷和智能化，以加快知识发现。在这里，我们介绍了由美国国家航空航天局的人工智能，机器学习和建模应用程序组织的研讨会的建议摘要，这些应用程序为这些空间生物学挑战提供了关键解决方案。在未来十年中，将人工智能融入太空生物学领域将深化天空效应的生物学理解，促进预测性建模和分析，支持最大自主和可重复的实验，并有效地管理星载数据和元数据，所有目标使生活能够在深空中茁壮成长。

A "heart attack" or myocardial infarction (MI), occurs when an artery supplying blood to the heart is abruptly occluded. The "gold standard" method for imaging MI is Cardiovascular Magnetic Resonance Imaging (MRI), with intravenously administered gadolinium-based contrast (late gadolinium enhancement). However, no "gold standard" fully automated method for the quantification of MI exists. In this work, we propose an end-to-end fully automatic system (MyI-Net) for the detection and quantification of MI in MRI images. This has the potential to reduce the uncertainty due to the technical variability across labs and inherent problems of the data and labels. Our system consists of four processing stages designed to maintain the flow of information across scales. First, features from raw MRI images are generated using feature extractors built on ResNet and MoblieNet architectures. This is followed by the Atrous Spatial Pyramid Pooling (ASPP) to produce spatial information at different scales to preserve more image context. High-level features from ASPP and initial low-level features are concatenated at the third stage and then passed to the fourth stage where spatial information is recovered via up-sampling to produce final image segmentation output into: i) background, ii) heart muscle, iii) blood and iv) scar areas. New models were compared with state-of-art models and manual quantification. Our models showed favorable performance in global segmentation and scar tissue detection relative to state-of-the-art work, including a four-fold better performance in matching scar pixels to contours produced by clinicians.

Migraine is a high-prevalence and disabling neurological disorder. However, information migraine management in real-world settings could be limited to traditional health information sources. In this paper, we (i) verify that there is substantial migraine-related chatter available on social media (Twitter and Reddit), self-reported by migraine sufferers; (ii) develop a platform-independent text classification system for automatically detecting self-reported migraine-related posts, and (iii) conduct analyses of the self-reported posts to assess the utility of social media for studying this problem. We manually annotated 5750 Twitter posts and 302 Reddit posts. Our system achieved an F1 score of 0.90 on Twitter and 0.93 on Reddit. Analysis of information posted by our 'migraine cohort' revealed the presence of a plethora of relevant information about migraine therapies and patient sentiments associated with them. Our study forms the foundation for conducting an in-depth analysis of migraine-related information using social media data.